Resveratrol Side Effects, Benefits, Dosage, and Research Information - My Resveratrol Experience

trans-Resveratrol and Bioavailability, the connection.

Why is bioavailability so important when it comes to trans-resveratrol? For starters if the "good parts" of a drug or supplement don't make it to the intended destination then there is no chance it is going to work.  We as humans metabolize ingested supplements at different rates.  It is necessary to make sure you are taking the proper dose and this can be different based on your own metabolism.  The faster your body metabolizes a supplement the less likely it is for the effective amount of that supplement to reach its intended destination at lower doses compared to a human with a lower metabolism.

Keep in mind that many non-human studies, especially those done with rats, are given at much higher doses of resv at approximately 50mg/KG of body weight.  Since rats have higher metabolisms then humans it is important we take a lower dose to get a similar effect.  This is described in more detail below...

Bioavailability, what does it have to do with Resveratrol?

I've always been known as someone who jumps into a project and digs deep.  I had no clue what I was getting into when I happened across resveratrol.  My research constantly creates more questions and more learning but you have to start some where.  A topic I found comes up often with those studying the effectiveness of resveratrol is "bioavailability."  Prior to getting into how bioavailability effects resveratrol users let's first start out by learning what it is.  Bioavailability is a part of the science of Pharmacokinetics.  Ok, so what is pharma-co-ka whatics now?