Resveratrol Side Effects, Benefits, Dosage, and Research Information - My Resveratrol Experience

Doctor's and Resveratrol: Some know, some don't!

For the most part, when it comes to this site and my resveratrol use, I keep it to myself.  Very few people in my "circle" know about the site or that I take supplements.  For me, I don't want to defend my decisions to use these products over and over again to the people I see every day.  I am willing to take the time to explain it to those who are open-minded and interested in learning more.  That is why I enjoy sharing my experiences on this site with like minded people.  At the same time there are a select few close friends whom I've shared this site and my resveratrol usage with.

Recently I was having dinner with my parents, my father who is 60, and my mother who is, well, we'll just say she is a little younger then him.  My father is a private pilot who has been flying for many years now.  Each year pilots have to get a mandatory physical completed by an FAA approved physician.  This year it just so happens he was speaking with this specific doctor who recommended he look into taking this "new" supplement.  The doctor informed him it has been shown in studies to help a wide variety of diseases and anti-aging illnesses, amongst other things.

I basically finished my fathers story by saying, "I bet I know what it was he suggested... resveratrol!"  To my fathers, and my own astonishment, it was exactly what he was talking about.  Now I have never mentioned this site to my father so when I pulled up the home page to show him he was rather surprised.  I guess the apple doesn't fall to far from the tree after all.  I was eager to share my knowledge and offer some tidbits of information. 

This got me thinking... 

trans-Resveratrol and Bioavailability, the connection.

Why is bioavailability so important when it comes to trans-resveratrol? For starters if the "good parts" of a drug or supplement don't make it to the intended destination then there is no chance it is going to work.  We as humans metabolize ingested supplements at different rates.  It is necessary to make sure you are taking the proper dose and this can be different based on your own metabolism.  The faster your body metabolizes a supplement the less likely it is for the effective amount of that supplement to reach its intended destination at lower doses compared to a human with a lower metabolism.

Keep in mind that many non-human studies, especially those done with rats, are given at much higher doses of resv at approximately 50mg/KG of body weight.  Since rats have higher metabolisms then humans it is important we take a lower dose to get a similar effect.  This is described in more detail below...

My First Week on Resveratrol!!

Friday, May 2nd, 2008, was my first experience with Resveratrol.  After a long search for what I felt to be the best brand (i'll go into more detail about my search a little later) I took my first capsule; a 500mg dose of 99% pure trans-resveratrol.  I must say, after all the research I had done I was excited to get started and see results.  Ok, so I didn't feel anything the first day.

The next two days I took the Resveratrol at 1:00pm both days.  This happened to be a weekend in which case I was off from working out those two days.  I was eager to feel something but again didn't notice...